Mouse CD155/PVR Protein (CD1-MM455)
Catalogue Number: CD1-MM455-KAT
CD1-MM455 Image
CD1-MM455 Image
CD1-MM455 Image
CD1-MM455 Image
CD1-MM455 Image
CD1-MM455 Image
The purity of Mouse CD155 is greater than 95% as determined by SEC-HPLC.
CD1-MM455 Image
Mouse CD155 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
CD1-MM455 Image
Mouse CD155, His Tag immobilized on CM5 Chip can bind Mouse TIGIT, His Tag with an affinity constant of 4.00 uM as determined in SPR assay (Biacore T200).
CD1-MM455 Image
Immobilized Mouse CD155, His Tag at 5ug/ml (100ul/Well) on the plate. Dose response curve for Mouse TIGIT, hFc Tag with the EC50 of 56.5ng/ml determined by ELISA (QC Test).
CD1-MM455 Image
Loaded Mouse CD155, His Tag on Anti-His-Biosensor can bind Rat TIGIT, mFc Tag with an affinity constant of 6.93 nM as determined in BLI assay (Gator® Prime).
| Manufacturer: | Kactus |
| Shelf Life: | 12 months |
| Molecular Weight: | The protein has a predicted MW of 35.9 kDa. Due to glycosylation, the protein migrates to 55-75 kDa based on Bis-Tris PAGE result. |
| Physical state: | Lyophilized |
| Type: | Other Recombinant Protein |
| Alias: | CD155; HVED; NECL5; Necl-5; nectin-like 5; PVR; PVS; Tage4; PVSFLJ25946; FLJ25946 |
| Host Cell: | HEK293 cells |
| Shipping Condition: | RT |
| Unit(s): | 100 ug, 500 ug |
| Application: | ELISA, WB |
Description
Description: CD155 is a cell surface adhesion molecule functioning in tumor cell migration, invasion, and metastasis, and not surprisingly, is also designated as a common tumor-associated antigen. CD155 is also recognized by NK cells to induce their cytotoxicity. CD155 is also commonly referred to as the "poliovirus receptor," or PVR.
Additional Text
Protein Tag
HIS Tag
Short Description
Recombinant Mouse CD155/PVR Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Asp29-Leu348.
UniProt ID
Q8K094-1
Storage Note
-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3 months after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Biological Activity
Immobilized Mouse CD155, His Tag at 0.5Oeg/ml (100Oel/Well) on the plate. Dose response curve for Mouse TIGIT, hFc Tag with the EC50 of 0.23Oeg/ml determined by ELISA. The affinity constant of 4.00 OeM as determined in SPR assay (Biacore T200). See testing image for detail.
Endotoxin
Less than 1 EU per µg by the LAL method.
CD1-MM455 Datasheet
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