Cynomolgus CD200/OX-2 Protein (CD2-CM120)
Catalogue Number: CD2-CM120-KAT
CD2-CM120 Image
CD2-CM120 Image
CD2-CM120 Image
CD2-CM120 Image
CD2-CM120 Image
Cynomolgus CD200 R1, His Tag immobilized on CM5 Chip can bind Cynomolgus CD200, His Tag with an affinity constant of 35.84 nM as determined in SPR assay (Biacore T200).
CD2-CM120 Image
The purity of Cynomolgus CD200 is greater than 95% as determined by SEC-HPLC.
CD2-CM120 Image
Cynomolgus CD200 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
CD2-CM120 Image
Immobilized Cynomolgus CD200, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Human CD200 R1, hFc Tag with the EC50 of 6.2ng/ml determined by ELISA (QC Test).
| Manufacturer: | Kactus |
| Shelf Life: | 12 months |
| Molecular Weight: | The protein has a predicted MW of 23.66 kDa. Due to glycosylation, the protein migrates to 45-55 kDa based on Bis-Tris PAGE result. |
| Physical state: | Lyophilized |
| Type: | Other Recombinant Protein |
| Alias: | CD200; MOX1; MOX2; My033; MRC; OX-2; OX2 |
| Host Cell: | HEK293 cells |
| Shipping Condition: | RT |
| Unit(s): | 100 ug, 500 ug |
| Application: | ELISA, WB |
Description
Description: CD200 and its receptors are highly expressed in the lung, on epithelial cells and leukocytes, and emerging evidence links dysregulation of the CD200 pathway with asthma. Moreover, pharmacological modulation of CD200 receptors was shown to improve clinical and inflammatory outcomes of preclinical asthma models.
Additional Text
Protein Tag
HIS Tag
Short Description
Recombinant Cynomolgus CD200/OX-2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln56-Gly257.
UniProt ID
A0A2K5TQS2
Storage Note
-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3 months after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Biological Activity
The affinity constant of 35.84 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Endotoxin
Less than 1 EU per µg by the LAL method.
CD2-CM120 MSDS
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