Biotinylated Human CD20/MS4A1 Protein (CD2-HE120B)

Catalogue Number: CD2-HE120B-KAT

Manufacturer:Kactus
Shelf Life:12 months
Molecular Weight:The protein has a predicted MW of 16.8 kDa same as Bis-Tris PAGE result.
Physical state:Liquid
Type:Protein - Conjugated
Alias:MS4A1;CD20;MS4A-1;B-lymphocyte surface antigen B1;Bp35;Leukocyte surface antigen Leu-16;Membrane-spanning 4-domains subfamily A member 11
Host Cell:E.coli
Shipping Condition:Dry Ice
Unit(s): 100 ug, 500 ug
Application: ELISA, WB

Description

Description: B-lymphocyte antigen CD20 or CD20 is an activated-glycosylated phosphoprotein expressed on the surface of all B-cells beginning at the pro-B phase (CD45R , CD117) and progressively increasing in concentration until maturity.CD20 is the target of the monoclonal antibodies rituximab, ocrelizumab, obinutuzumab, ofatumumab, ibritumomab tiuxetan, tositumomab, and ublituximab, which are all active agents in the treatment of all B cell lymphomas, leukemias, and B cell-mediated autoimmune diseases.

Additional Text

Protein Tag

HIS-AviTag™

Short Description

Recombinant Biotinylated Human CD20/MS4A1 Protein is expressed from E.coli with His tag and Avi tag at the C-Terminus.It contains Ile141-Ser188.

Storage Note

Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

UniProt ID

P11836-1

Biological Activity

Immobilized Biotinylated Human CD20, His Tag at 1Oeg/ml (100Oel/well) on the streptavidin precoated plate (5Oeg/ml). Dose response curve for Anti-CD20 Antibody, hFc Tag with the EC50 of 87.3ng/ml determined by ELISA. See testing image for detail.

Endotoxin

Less than 1 EU per µg by the LAL method.

Price
£413.00


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