Cynomolgus CD3E&CD3D/CD3 epsilon&CD3 delta Protein (CD3-CM201)

Catalogue Number: CD3-CM201-KAT

Manufacturer:	Kactus
Shelf Life:	12 months
Molecular Weight:	The protein has a predicted MW of 36.9 kDa (CD3E) and 35.4 kDa (CD3D). Due to glycosylation,the protein migrates to 58-62 kDa (CD3E) and 44-46 kDa (CD3D) based on Bis-Tris PAGE result.
Physical state:	Lyophilized
Type:	Other Recombinant Protein
Alias:	CD3; CD3e; CD3E; CD3d; T3D; CD3D; CD3E&CD3D; CD3 delta&CD3 epsilon
Host Cell:	HEK293 cells
Shipping Condition:	RT
Unit(s):	100 ug, 500 ug
Application:	ELISA, WB

Overview
Datasheets

Description

Description: T-cell surface glycoprotein CD3 epsilon&CD3 delta chain, also known as CD3E&CD3D, are single-pass type I membrane proteins. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain.

Additional Text

Gene Name

CD3D

Gene ID

102133701

Protein Tag

hFC Tag

Uniprot ID

Q95LI5.2, Q95LI8

Storage Note

-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3 months after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Biological Activity

Immobilized Cynomolgus CD3E&CD3D, hFc Tag at 0.5Oeg/ml (100Oel/Well). Dose response curve for Biotinylated Anti-CD3E&CD3D Antibody, mFc Tag with EC50 of 13.9ng/ml determined by ELISA. See testing image for detail.

Endotoxin

Less than 1 EU per µg by the LAL method.

Short Description

Recombinant Cynomolgus CD3E&CD3D/CD3 epsilon&CD3 delta Protein is expressed from HEK293 with hFc tag at the C-Terminus of CD3E and CD3D.; It contains Gln22-Asp117 (CD3E) and Phe22-Ala105 (CD3D).

CD3-CM201 Datasheet

CD3-CM201 MSDS

Price

£259.00

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