Human CD3E&CD3G/CD3 epsilon&CD3 gamma Protein (CD3-HM257)

Catalogue Number: CD3-HM257-KAT

Manufacturer:	Kactus
Shelf Life:	12 months
Molecular Weight:	The protein has a predicted MW of 37.8 kDa (CD3E) and 36.5 kDa (CD3G). Due to glycosylation, the protein migrates to 40-60 kDa based on Bis-Tris PAGE result.
Physical state:	Lyophilized
Type:	Other Recombinant Protein
Host Cell:	HEK293 cells
Shipping Condition:	RT
Unit(s):	100 ug, 500 ug
Application:	ELISA, WB

Overview
Datasheets

Description

Description: T-cell surface glycoprotein CD3 epsilon & CD3 gamma chain, also known as CD3E&CD3G, are single-pass type I membrane proteins. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain.

Additional Text

Protein Tag

hFC Tag

Uniprot ID

P07766, P09693

Gene ID

916; 917

Gene Name

CD3E, CD3G

Storage Note

-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3 months after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Biological Activity

Immobilized Human CD3E&CD3G, hFc Tag at 0.5Oeg/ml (100Oel/Well). Dose response curve for Biotinylated Anti-CD3E&CD3G Ab.1, hFc Tag with the EC50 of 1.22ug/ml determined by ELISA. See testing image for detail.

Endotoxin

Less than 1 EU per µg by the LAL method.

Short Description

Recombinant Human CD3E&CD3G/CD3 epsilon&CD3 gamma Protein is expressed from HEK293 with hFc tag at the C-Terminus of CD3E and CD3G.It contains Asp23-Asp126 (CD3E) and Gln23-Ser116 (CD3G).

Specificity

CD3; CD3 epsilon; CD3epsilon; CD3ε; CD3 ε; CD3E; CD3e; CD3 gamma; CD3gamma; CD3γ; CD3 γ; CD3G; CD3g; CD3epsilon&CD3gamma; CD3 epsilon&CD3 gamma; CD3 epsilon & CD3 gamma; CD3ε&CD3γ; CD3 ε&CD3 γ; CD3 ε & CD3 γ; CD3E&CD3G; CD3E & CD3G; CD3 E & CD3 G; CD3e&CD3g; CD3e & CD3g; CD3 e & CD3 g

CD3-HM257 Datasheet

CD3-HM257 MSDS

Price

£259.00

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Quantity
Unit Size

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