Canine CD46 Protein (CD4-DM146)
Catalogue Number: CD4-DM146-KAT
| Manufacturer: | Kactus |
| Shelf Life: | 12 months |
| Molecular Weight: | The protein has a predicted MW of 34.11 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Bis-Tris PAGE result. |
| Physical state: | Lyophilized |
| Type: | Other Recombinant Protein |
| Alias: | TLX; CD46; MCP; MIC10; AHUS2; TRA2.10; Membrane cofactor; LOC609365 |
| Host Cell: | HEK293 cells |
| Shipping Condition: | RT |
| Unit(s): | 100 ug, 500 ug |
| Application: | WB |
Description
Description: CD46 was discovered in 1986 during a search for novel C3b-binding proteins. CD46 is expressed ubiquitously and functions as a co-factor in the factor I-mediated proteolytic cleavage of C3b and C4b. Its vital role in preventing complement deposition on host tissue is underpinned by the fact that deficiency of CD46 is a predisposing factor for numerous disease conditions arising from complement-mediated 'self-attack'.
Additional Text
Protein Tag
HIS Tag
Gene ID
609365
Gene Name
LOC609365
Short Description
Recombinant Canine CD46 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Cys45-Gly344.
UniProt ID
A0A8C0YZN5
Storage Note
-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3 months after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Endotoxin
Less than 1 EU per µg by the LAL method.
CD4-DM146 Datasheet
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