Human CD4/LEU3 Protein (CD4-HM204)

Catalogue Number: CD4-HM204-KAT

Manufacturer:Kactus
Shelf Life:12 months
Molecular Weight:The protein has a predicted MW of 67.5 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Bis-Tris PAGE result.
Physical state:Lyophilized
Type:Other Recombinant Protein
Alias:CD4 antigen (p55); CD4 molecule; CD4 receptor; CD4; CD4mut; EU3
Host Cell:HEK293 cells
Shipping Condition:RT
Unit(s): 100 ug, 500 ug
Application: ELISA, WB

Description

Description: CD4, also known as L3T4, T4, and W3/25, is an approximately 55 kDa type I transmembrane glycoprotein that is expressed predominantly on thymocytes and a subset of mature T lymphocytes. It is a standard phenotype marker for the identification of T cell populations.Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex.

Additional Text

Gene Name

CD4

Gene ID

920

Uniprot ID

P01730

Protein Tag

hFC Tag

Short Description

Recombinant Human CD4/LEU3 Protein is expressed from HEK293 with hFc at the C-Terminus.It contains Lys26-Trp390.

Storage Note

-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3 months after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Biological Activity

Immobilized Human CD4 at 0.5Oeg/ml (100Oel/Well) on the plate. Dose response curve for Biotinylated Anti-CD4 Antibody, hFc Tag with the EC50 of 20.9ng/ml determined by ELISA. See testing image for detail.

Endotoxin

Less than 1 EU per µg by the LAL method.

Price
£153.00


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