CD5, human

Catalogue Number: CD5-2-1-EXA

Manufacturer:ExAlpha
Type:Monoclonal Primary Antibody - Unconjugated
Shipping Condition:RT
Storage Condition:2-8°C
Unit(s): 1 ml
Host name: Rabbit
Clone: EP77
Isotype: IgG
Immunogen: Synthetic Protein, corresponding to a sequence of human CD5 molecule
Application: FC, IHC-P, IHC-Fr

Description

Description: The antibody to CD5 is used for the classification of lymphoid neoplasm. CD5 is exprimed by the majority of T-cell lymphoma and is also found on B-cells in some cases of chronic lymphatic leukaemia and centrocytic lymphoma. Normally it is not found in other forms of lymphoid neoplasm e.g. follicular lymphoma, Hairy Cell Lymphoma and Large Cell Lymphoma. CD5 is a lymphocyte surface molecule with a molecular weight of 67 kDa. It is exprimed by 95% of thymocytes and app. 72% of peripheral blood lymphocytes. In lymph nodes the antigen is detected in the T-cell region mainly. CD5 is over-expressed in leukaemia and T-cell lymphoma and may also be detected in a subpopulation of activated B-cells. Human CD5 molecule.

Additional Text

Gene ID

921

Gene Name

CD5

Uniprot ID

P06127

Antibody Clonality

Monoclonal

Storage Note

2-8°C

Application Notes

IHC(C, P), FACS