Biotinylated Human IL-2 R alpha/CD25 Protein (CD5-HM425B)
Catalogue Number: CD5-HM425B-KAT
CD5-HM425B Image
CD5-HM425B Image
CD5-HM425B Image
CD5-HM425B Image
The purity of Biotinylated Human IL-2 R alpha is greater than 95% as determined by SEC-HPLC.
CD5-HM425B Image
Biotinylated Human IL-2 R alpha on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
CD5-HM425B Image
Immobilized Biotinylated Human IL-2 R alpha, His Avi Tag at 0.5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-IL-2 R alpha Antibody, hFc Tag with the EC50 of 3.9 ng/ml determined by ELISA (QC Test).
| Manufacturer: | Kactus |
| Shelf Life: | 12 months |
| Molecular Weight: | The protein has a predicted MW of 24.6 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Bis-Tris PAGE result. |
| Physical state: | Lyophilized |
| Type: | Protein - Conjugated |
| Alias: | CD25; IDDM10; IL-2 R alpha; IL2R; IL2RA; p55; TCGFR |
| Host Cell: | HEK293 cells |
| Shipping Condition: | RT |
| Unit(s): | 100 ug, 500 ug |
| Application: | ELISA, WB |
Description
Description: Human IL-2 receptor alpha (IL-2 R alpha), also known as Tac antigen and as CD25, was initially identified as a 55 kDa membrane glycoprotein that is capable of binding IL-2.eceptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells.
Additional Text
Gene Name
IL2RA
Gene ID
3559
Uniprot ID
P01589
Protein Tag
HIS-AviTag™
Short Description
Recombinant Biotinylated Human IL-2 R alpha/CD25 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Glu22-Cys213.
Storage Note
-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3 months after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Biological Activity
Immobilized Anti-CD25 Antibody, hFc Tag at 0.2Oeg/ml (100Oel/well) on the plate. Dose response curve for Biotinylated Human IL-2 R alpha, His Tag with the EC50 of 11.9ng/ml determined by ELISA. See testing image for detail.
Endotoxin
Less than 1 EU per µg by the LAL method.
CD5-HM425B Datasheet
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations