CD68 (KP1) Macrophages, human

Catalogue Number: CD68KP1-0.5-EXA

Manufacturer:ExAlpha
Type:Monoclonal Primary Antibody - Unconjugated
Shipping Condition:RT
Storage Condition:2-8°C
Unit(s): 0.5 ml
Host name: Mouse
Clone: KP1
Isotype: IgG1, kappa
Immunogen: Subcellular fraction of human alveolar macrophages
Application: IHC-P, IHC-Fr

Description

Description: The antibody KP1 is well suited for the detection of tissue macrophages including Kupffer cells and spleen macrophages. CD68 is expressed on macrophages and monocytes. KP-1 is important for identifying macrophages in tissue sections. It stains macrophages in a wide variety of human tissues, including Kupffer cells and macrophages in the red pulp of the spleen, in lamina propria of the gut, in lung alveoli, and in bone marrow. KP-1 reacts with myeloid precursors and peripheral blood granulocytes. It also reacts with plasmacytoid T cells which are supposed to be of monocyte/macrophage origin. It shows strong granular cytoplasmic staining of chronic and acute myeloid leukemia and also reacts with rare cases of true histiocytic neoplasia. Tumors of lymphoid origin are usually not stained. CD68 transmembran glycoprotein MW 110 kDa, localised in macrophages.

Additional Text

Purification

Purified

Antibody Clonality

Monoclonal

Storage Note

2-8°C

Application Notes

IHC(C, P)