Human CD74/DHLAG Protein (CD7-HM175)

Catalogue Number: CD7-HM175-KAT

Manufacturer:	Kactus
Shelf Life:	24 months
Molecular Weight:	The protein has a predicted MW of 19.1 kDa. Due to glycosylation, the protein migrates to 30-40 kDa based on Bis-Tris PAGE result.
Physical state:	Lyophilized
Type:	Other Recombinant Protein
Alias:	CD74; Ii; DHLAG; HLADG; Ia-GAMMA; p33; CLIP; INVG34; Ia GAMMA ; II
Host Cell:	HEK293 cells
Shipping Condition:	RT
Unit(s):	100 ug, 500 ug
Application:	ELISA, WB

Overview
Datasheets

Description

Description: CD74 (invariant MHC class II) regulates protein trafficking and is a receptor for macrophage migration inhibitory factor (MIF) and d-dopachrome tautomerase (d-DT/MIF-2). CD74 expression is increased in tubular cells and/or glomerular podocytes and parietal cells in human metabolic nephropathies, polycystic kidney disease, graft rejection and kidney cancer and in experimental diabetic nephropathy and glomerulonephritis.

Additional Text

Protein Tag

HIS Tag

Accession Number

NP_004346.1

Short Description

Recombinant Human CD74/DHLAG Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Gln73-Met232.

Storage Note

-20 to -80°C for 24 months as supplied from date of receipt.; -80°C for 3 months after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Biological Activity

Immobilized Human CD74 at 0.5Oeg/ml (100Oel/Well) on the plate. Dose response curve for Anti-CD74 Antibody, hFc Tag with the EC50 of 10.6ng/ml determined by ELISA. See testing image for detail.

Endotoxin

Less than 1 EU per µg by the LAL method.

CD7-HM175 Datasheet

CD7-HM175 MSDS

Price

£189.00

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