Human IL-17R alpha/CD217 Protein (CD7-HM1RA)
Catalogue Number: CD7-HM1RA-KAT
CD7-HM1RA Image
CD7-HM1RA Image
CD7-HM1RA Image
CD7-HM1RA Image
CD7-HM1RA Image
Human IL-17R alpha, His Tag immobilized on CM5 Chip can bind Human IL-17A, His Tag with an affinity constant of 1.57 nM as determined in SPR assay (Biacore T200).
CD7-HM1RA Image
The purity of Human IL-17R alpha is greater than 95% as determined by SEC-HPLC.
CD7-HM1RA Image
Human IL-17R alpha on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
CD7-HM1RA Image
Immobilized Human IL-17R alpha, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human IL-17A, His Tag with the EC50 of 0.44ug/ml determined by ELISA (QC Test).
| Manufacturer: | Kactus |
| Shelf Life: | 12 months |
| Molecular Weight: | The protein has a predicted MW of 34.6 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result. |
| Physical state: | Lyophilized |
| Type: | Other Recombinant Protein |
| Alias: | CD217; CDw217; IL-17RA; IL17R; CANDF5; IL-17R; IL-17R-alpha; IL17Rα |
| Host Cell: | HEK293 cells |
| Shipping Condition: | RT |
| Unit(s): | 100 ug, 500 ug |
| Application: | ELISA, WB |
Description
Description: Interleukin 17 (also known as CTLA-8) is a T cell-expressed pleotropic cytokine. IL-17 binds to IL-17 receptor (IL-17 R) which shares no homology with any known family of receptors. While the expression of IL-17 is restricted to activated T cells, the IL-17 R mRNA exhibits a broad tissue distribution, and has been detected in virtually all cells and tissues tested. The human IL-17 R gene was localized to chromosome 22.
Additional Text
Protein Tag
HIS Tag
Short Description
Recombinant Human IL-17R alpha/CD217 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu33-Trp320.
UniProt ID
Q96F46-1
Storage Note
-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3 months after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Biological Activity
Immobilized Human IL-17R alpha, His Tag at 2Oeg/ml (100Oel/well) on the plate. Dose response curve for Biotinylated Human IL-17A, His Tag with the EC50 of 0.15Oeg/ml determined by ELISA. The affinity constant of 1.57 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Endotoxin
Less than 1 EU per ug by the LAL method.
CD7-HM1RA Datasheet
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