Human IL-17R alpha/CD217 Protein (CD7-HM2RA)

Catalogue Number: CD7-HM2RA-KAT

Manufacturer:	Kactus
Shelf Life:	12 months
Molecular Weight:	The protein has a predicted MW of 60.2 kDa. Due to glycosylation, the protein migrates to 75-90 kDa based on Bis-Tris PAGE result.
Physical state:	Lyophilized
Type:	Other Recombinant Protein
Alias:	CD217; CDw217; IL-17RA; IL17R; CANDF5; IL-17R; IL-17R-alpha; IL17Rα
Host Cell:	HEK293 cells
Shipping Condition:	RT
Unit(s):	100 ug, 500 ug
Application:	ELISA, WB

Overview
Datasheets

Description

Description: Interleukin 17 (also known as CTLA-8) is a T cell-expressed pleotropic cytokine. IL-17 binds to IL-17 receptor (IL-17 R) which shares no homology with any known family of receptors. While the expression of IL-17 is restricted to activated T cells, the IL-17 R mRNA exhibits a broad tissue distribution, and has been detected in virtually all cells and tissues tested. The human IL-17 R gene was localized to chromosome 22.

Additional Text

Protein Tag

hFC Tag

Short Description

Recombinant Human IL-17R alpha/CD217 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Leu33-Trp320.

UniProt ID

Q96F46-1

Storage Note

-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3 months after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Biological Activity

Immobilized Human IL-17A, His Tag at 0.5Oeg/ml (100Oel/well) on the plate. Dose response curve for Human IL-17R alpha, hFc Tag with the EC50 of 66.6ng/ml determined by ELISA. The affinity constant of 2.18 nM as determined in SPR assay (Biacore T200). See testing image for detail.

Endotoxin

Less than 1 EU per ug by the LAL method.

CD7-HM2RA Datasheet

CD7-HM2RA MSDS

Price

£106.00

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Quantity
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