Human CD79B Protein (CD7-HM49B)

Catalogue Number: CD7-HM49B-KAT

Manufacturer:Kactus
Shelf Life:12 months
Molecular Weight:The protein has a predicted MW of 18.1 kDa. Due to glycosylation, the protein migrates to 33-42 kDa based on Bis-Tris PAGE result.
Physical state:Lyophilized
Type:Other Recombinant Protein
Alias:B29; CD79b molecule; CD79B; IGB; IGBAGM6; Ig-beta; Ig-β
Host Cell:HEK293 cells
Shipping Condition:RT
Unit(s): 100 ug, 500 ug
Application: ELISA, WB

Description

Description: CD79B (also known as B29, Ig beta and B cell antigen receptor complex-associated protein beta-chain) is a 36-40 kDa member of the Ig-Superfamily. It is required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation.

Additional Text

Protein Tag

HIS-AviTag™

Short Description

Recombinant Human CD79B Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Ala29-Asp159.

UniProt ID

P40259-1

Storage Note

-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3 months after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Biological Activity

Immobilized Human CD79B, His Tag at 0.5Oeg/ml (100Oel/Well). Dose response curve for Anti-CD79B Antibody, hFc Tag with the EC50 of 5.8ng/ml determined by ELISA. See testing image for detail.

Endotoxin

Less than 1 EU per µg by the LAL method.

Price
£212.00


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