Biotinylated Human CD93/C1q R1 Protein (CD9-HM493B)
Catalogue Number: CD9-HM493B-KAT
CD9-HM493B Image
CD9-HM493B Image
CD9-HM493B Image
CD9-HM493B Image
CD9-HM493B Image
The purity of Biotinylated Human CD93 is greater than 95% as determined by SEC-HPLC.
CD9-HM493B Image
Biotinylated Human CD93 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
CD9-HM493B Image
Biotinylated Human CD93, His-Avi Tag immobilized on CM5 Chip can bind Human IGFBP-7, His Tag with an affinity constant of 0.17 uM as determined in SPR assay (Biacore T200).
CD9-HM493B Image
Immobilized Biotinylated Human CD93, His-Avi Tag at 2ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Human IGFBP7, hFc Tag with the EC50 of 29.8ng/ml determined by ELISA (QC Test).
| Manufacturer: | Kactus |
| Shelf Life: | 24 months |
| Molecular Weight: | The protein has a predicted MW of 61.2 kDa. Due to glycosylation, the protein migrates to 90-110 kDa based on Bis-Tris PAGE result. |
| Physical state: | Lyophilized |
| Type: | Protein - Conjugated |
| Alias: | C1q/MBL/SPA receptor; C1qR; C1qR(p); C1qRp; CDw93; CD93; C1QR1; MXRA4; ECSM3; dJ737E23.1 |
| Host Cell: | HEK293 cells |
| Shipping Condition: | RT |
| Unit(s): | 100 ug, 500 ug |
| Application: | ELISA, WB |
Description
Description: CD93 has been shown critical roles in inflammatory and immune diseases. CD93 silencing increased IL-6 and TSLP, but not IL-33 levels in culture supernatants. HDM-induced asthma mice showed significant airway hyperresponsiveness and inflammation with Th2 cytokine activation, along with decreased CD93 expression in bronchial epithelial cells and lung homogenates but increased serum CD93 levels.
Additional Text
Gene ID
22918
Gene Name
CD93
Uniprot ID
Q9NPY3
Protein Tag
HIS-AviTag™
Short Description
Recombinant Biotinylated Human CD93/C1q R1 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Thr22-Lys580.
Storage Note
-20 to -80°C for 24 months as supplied from date of receipt.; -80°C for 3 months after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Biological Activity
The affinity constant of 0.17 OeM as determined in SPR assay (Biacore T200). See testing image for detail.
Endotoxin
Less than 1 EU per µg by the LAL method.
CD9-HM493B Datasheet
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