Pan-Cytokeratin, 2 Clones (AE1/AE3)

Catalogue Number: CK102-EXA

Manufacturer:ExAlpha
Type:Monoclonal Primary Antibody - Unconjugated
Shipping Condition:RT
Storage Condition:2-8°C
Unit(s): 1 ml
Host name: Mouse
Clone: AE1/AE3
Isotype: IgG1
Immunogen: Human epithelial keratins
Application: IHC-P, IHC-Fr

Description

Description: Pan-Cytokeratin (AE1/AE3) contains two different clones, which label the majority of normal epithelia and carcinoma. Cytokeratins are a group of water soluble filament proteins, which are components of the cytoskeleton of the epidermis and other epithelial cells. Gelelectrophoretic investigation revealed 20 different Cytokeratins, characterised by different molecular sizes and pI-values. They can be subdivided into basic and acid subfamilies. The nomenclature according to Moll et al. (1982) is most commonly used. Basic cytokeratins (52-67 kD) and acid cytokeratins (40, 48, 50, 50', 56,5 kD) CK 1-8, 10, 14-16 and 19 according to the nomenclature by Moll (1982) .

Additional Text

Concentration

70 ug/ml

Antibody Clonality

Monoclonal

Storage Note

2-8°C

Application Notes

IHC(C, P)