Cytokeratin 14

Catalogue Number: CK114-EXA

Manufacturer:ExAlpha
Type:Monoclonal Primary Antibody - Unconjugated
Shipping Condition:RT
Storage Condition:2-8°C
Unit(s): 1 ml
Host name: Mouse
Clone: LL002
Isotype: IgG3
Immunogen: C-terminal 15-AA peptide of cytokeratin 14 conjugated to thyroglobulin
Application: IHC-P, IHC-Fr

Description

Description: Cytokeratin 14 (CK14) belongs to the acid subfamily of CKs (Type I) and is characteristic of stratifying epithelia (trachea, bronchi, cervix, epidermis, sweat glands). The antibody to CK14 is helpful to distinguish between stratifying epithelia and simple epithelia, which don't express this type of cytokeratins. Tumours of squamous cell origin will be stained with this antibody. Cytokeratins are a group of water-insoluble filamentous proteins. They are constituents of the cytoskeleton of epidermal cells and other epithelial cells. Up to now 20 different cytokeratins have been characterised by gel electrophoresis. They have been subdivided into a basic and an acid subfamily. Most frequently the nomenclature according to Moll et al. (1982) is used. Human cytokeratin 14.

Additional Text

Gene ID

3861

Gene Name

KRT14

Uniprot ID

P02533

Concentration

40 ug/ml

Antibody Clonality

Monoclonal

Storage Note

2-8°C

Application Notes

IHC(C, P)