Cytokeratin 7
Catalogue Number: CK507-EXA
| Manufacturer: | ExAlpha |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Shipping Condition: | RT |
| Storage Condition: | 2-8°C |
| Unit(s): | 5 ml |
| Host name: | Mouse |
| Clone: | OV-TL12/30 |
| Isotype: | IgG1 |
| Immunogen: | Ovarian carcinoma cell line OTN 11 |
| Application: | IHC-P, IHC-Fr |
Description
Description: Cytokeratin 7 is a basic filament protein, which is exprimed by many epithelial cells, especially those of the ductal and glandular types. The antibody doesn't react with squamous epithelia but with transitional cell epithelia of the urinary tract. Epithelia of the lung and breast are positive while colon and prostate remain unstained. The antibody is helpful for the differentiation of colon and ovarian cancer cells in ascites. Cytokeratins are a group of water soluble filament proteins, which are components of the cytoskeleton of the epidermis and other epithelial cells. Gel-electrophoretic investigation revealed 20 different Cytokeratins, characterised by different molecular sizes and pI-values. They can be subdivided into basic and acid subfamilies. The nomenclature according to Moll et al. (1982) is most commonly used. Basic Cytokeratin, 54 kD, CK 7 (Moll).
Additional Text
Gene Name
KRT7
Gene ID
3855
Uniprot ID
P08729
Antibody Clonality
Monoclonal
Storage Note
2-8°C
Application Notes
IHC(C, P)
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations