Cynomolgus Claudin 6 Protein-VLP (CLD-CM006)

Catalogue Number: CLD-CM006-KAT

Manufacturer:Kactus
Shelf Life:12 months
Molecular Weight:The target protein has a predicted MW of 24.60 kDa.
Physical state:Liquid
Type:Other Recombinant Protein
Alias:Claudin-6; Skullin; CLDN6; Claudin6; Skullin 2; EGM_11390; Claudin
Host Cell:HEK293 cells
Shipping Condition:Dry Ice
Unit(s): 100 ug
Application: ELISA

Description

Description: Claudin-6 is a multipass transmembrane protein in the Claudin family. Claudin-6 is expressed by epithelial cells where it participates in tissue development and the maintenance of tight junction integrity. Human Claudin-6 shares 88% and 86% amino acid sequence identity with mouse and rat Claudin-6, respectively.

Additional Text

Gene Name

CLDN6

Gene ID

102140361

Storage Note

Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

UniProt ID

G7Q0B0

Biological Activity

Immobilized Cynomolgus Claudin 6 VLP at 5Oeg/ml (100Oel/Well) on the plate. Dose response curve for Anti-Claudin6 Antibody, mFc Tag with the EC50 of 4ng/ml determined by ELISA. The affinity constant of 0.85 nM as determined in SPR assay (Biacore T200). See testing image for detail.

Endotoxin

Less than 1 EU per µg by the LAL method.

Short Description

Recombinant Cynomolgus Claudin 6 Protein-VLP is expressed from HEK293.It contains Met1-Val220 (It may have cross reaction with anti-His antibody).