Biotinylated Human Claudin 6 Protein-VLP (CLD-HM006B)
Catalogue Number: CLD-HM006B-KAT
CLD-HM006B Image
CLD-HM006B Image
CLD-HM006B Image
CLD-HM006B Image
CLD-HM006B Image
The purity of Biotinylated Human Claudin 6 VLP is greater than 95% as determined by SEC-HPLC.
CLD-HM006B Image
Biotinylated Human Claudin 6 VLP captured on CM5 Chip via streptavidin can bind Anti-Claudin 6 Antibody with an affinity constant of 0.46 nM as determined in SPR assay (Biacore T200).
CLD-HM006B Image
Immobilized Biotinylated Human Claudin 6 VLP at 5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-Claudin6 Antibody, mFc Tag with the EC50 of 6.5ng/ml determined by ELISA (QC Test).
CLD-HM006B Image
Loaded Biotinylated Human Claudin 6 VLP on Streptavidin-Biosensor can bind Anti-Claudin 6 Antibody, hFc Tag with an affinity constant of 1.46 nM as determined in BLI assay (Gator® Prime).
| Manufacturer: | Kactus |
| Shelf Life: | 6 months |
| Molecular Weight: | The target protein has a predicted MW of 24.5 kDa. |
| Physical state: | Liquid |
| Type: | Protein - Conjugated |
| Alias: | Claudin-6; Skullin; CLDN6; Claudin6; Skullin 2 |
| Host Cell: | HEK293 cells |
| Shipping Condition: | Dry Ice |
| Unit(s): | 100 ul |
Description
Description: Claudin-6 is a multipass transmembrane protein in the Claudin family. Claudin-6 is expressed by epithelial cells where it participates in tissue development and the maintenance of tight junction integrity. Human Claudin-6 shares 88% and 86% amino acid sequence identity with mouse and rat Claudin-6, respectively.
Additional Text
Gene Name
CLDN6
Uniprot ID
P56747
Gene ID
9074
Storage Note
Valid for 6 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Biological Activity
The affinity constant of 0.65 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Endotoxin
Less than 1 EU per µg by the LAL method.
Short Description
Recombinant Biotinylated Full length Human Claudin 6 Protein-VLP is expressed from HEK293.It contains Met1-Val220 (It may have cross reaction with anti-His antibody).
CLD-HM006B Datasheet
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