Biotinylated Human CLEC12A/MICL/CLL-1 Protein (CLE-HM42AB)

Catalogue Number: CLE-HM42AB-KAT

Manufacturer:Kactus
Shelf Life:12 months
Molecular Weight:The protein has a predicted MW of 26.4 kDa. Due to glycosylation, the protein migrates to 38-50 kDa based on Bis-Tris PAGE result.
Physical state:Lyophilized
Type:Protein - Conjugated
Alias:MICL; CLL-1; CLEC12A; CLL1; DCAL2; DCAL-2; CD371; CD303; CLECSF11; CLECSF7; DLEC; HECL; PRO34150; DCAL-2
Host Cell:HEK293 cells
Shipping Condition:RT
Unit(s): 100 ug, 500 ug
Application: ELISA, WB

Description

Description: CLEC12A has recently been identified as an antigen, expressed on leukemic stem cells and leukemic blasts. Given the fact that this expression profile seems stable throughout diagnosis, treatment and relapse on leukemic blasts and leukemic stem cells, CLEC12A can be considered a highly potent and reliable marker for the detection of measurable residual disease and therefore applicable for risk stratification and prognostication in AML.

Additional Text

Protein Tag

AviTag™, HIS Tag

Uniprot ID

Q5QGZ9-2

Short Description

Recombinant Biotinylated Human CLEC12A/MICL/CLL-1 Protein is expressed from HEK293 with His tag at the N-Terminus and Avi tag at the C-Terminus.It contains His65-Ala265.

Storage Note

-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3 months after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Biological Activity

Immobilized Anti-CLEC12A Antibody, hFc Tag at 1Oeg/ml (100Oel/well) on the plate. Dose response curve for Biotinylated Human CLEC12A, His Tag with the EC50 of 0.41Oeg/ml determined by ELISA. See testing image for detail.

Endotoxin

Less than 1 EU per µg by the LAL method.

Price
£413.00


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