Catalogue Number: CLK-1010-1G-JEN
Manufacturer: | Jena Bioscience |
Shelf Life: | 12 months |
Physical state: | solid |
Type: | Conjugation Reagent |
Shipping Condition: | RT |
Storage Condition: | 2-8°C |
Unit(s): | 1 g |
Description: THPTA is a water-soluble, very effective ligand for Cu(I)-catalyzed Alkyne-Azide click chemistry reactions (CuAAC). It serves a dual purpose: 1) Accelaration of the CuAAC reaction by maintaining the Cu(I) oxidation state of copper sources and 2) Protection of biomolecules from oxidative damage during the labeling reaction[1,2]. THPTA is a superior alternative to water-insoluble TBTA. A stock solution can be prepared in ddH2O and subsequently be stored at -20°C. Avoid freeze-thaw cycles. Presolski et al.[1] and Hong et al.[2] provide a general protocol for CuAAC reactions that may be used as a starting point for the set up and optimization of individual assays.
water, DMSO, DMF, MeOH
N(Cc1nnn(c1)CCCO)(Cc1nnn(c1)CCCO)Cc1cn(nn1)CCCO