N6-Propargyl-ATP (N6pATP)

Catalogue Number: CLK-NU-001-1-JEN

Manufacturer:	Jena Bioscience
Shelf Life:	12 months
Physical state:	solid
Type:	Conjugation Reagent
Shipping Condition:	Blue Ice
Unit(s):	1 mg
Application:	Cnjg

Overview
Datasheets

Additional Text

Solubility

10 mM Tris-HCl pH 7.5

Additional Information

Please note: This compound contains a phosphoramide linkage which is hydrolyzed at pH

Application Notes

in vitro AMPylation of proteins[1,2] in vitro polyadenylation of RNA[3] The resulting alkyne-functionalized protein[1,2] or RNA[3] can subsequently be processed via Cu(I)-catalyzed (azide-alkyne) click chemistry that offers the choiceto introduce a Biotin group for subsequent purification tasks (via Azides of Biotin)to introduce fluorescent group for subsequent microscopic imaging (via Azides of fluorescent dyes)to crosslink the RNA to azide-functionalized biomolecules e.g.proteins Presolski et al.[4] and Hong et al.[5] provide a general protocol for Cu(I)-catalyzed click chemistry reactions that may be used as a starting point for the set up and optimization of individual assays. Agonistic ligand, mainly for nucleoside receptor A1 Nucleoside-triphosphates can be converted by different membrane-bound phosphatases into nucleosides acting as nucleoside receptor ligands. In some cases nucleoside phosphates act also directly on nucleoside receptors.

Short Description

N6-Propargyl-adenosine-5'-triphosphate, Sodium salt

Smile String

O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(=O)(OP(=O)(OP(=O)(O)O)O)O)n1c2c(c(ncn2)NCC#C)nc1

CLK-NU-001-1 MSDS

CLK-NU-001-1 Datasheet

Price

£129.00

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