5/6-Carboxyrhodamine 110-PEG4-Alkyne, Abs/Em = 501/525 nm, Acetylene-Fluor 488

Catalogue Number: CLK-TA106-25-JEN

Manufacturer:Jena Bioscience
Shelf Life:12 months
Molecular Formula:C32H33N3O8
Physical state:solid
Type:Fluorescent Reagents
Shipping Condition:RT
Unit(s): 25 mg

Description

Description: With excitation maximum at 501 nm, the acetylene - carboxyrhodamine 110 conjugate is an excellent match to the intense 488 nm spectral line of the argon ion laser commonly used in many confocal laser-scanning microscopes. Carboxyrhodamine 110-PEG4-alkyne is an excellent green fluorescent rhodamine dye. The conjugate has better solubility than the parent dye carboxyrhodamine and its long PEG4 spacer should reduce any steric effect of the dye on the molecule to be labeled. Carboxyrhodamine 110 and its derivatives are, in general, significantly more photostable than any other known green fluorescent dyes including Alexa 488. In addition, the fluorescence of the acetylene-PEG4-carboxyrhodamine 110 conjugate is completely insensitive to pH between 4 and 9. Unlike Alexa 488, which is readily degraded under alkaline condition, carboxyrhodamine 110 and its derivatives are highly stable under both acidic and basic conditions. As a result, carboxyrhodamine 110 and its derivatives are superior alternatives to other green fluorescent dyes.

Additional Text

Solubility

DMF, DMSO, MeOH

Smile String

O(CCOCCOCCOCCNC(=O)c1cc(c2c3ccc(cc3oc3cc(=[NH2+])ccc23)N)c(cc1)C(=O)[O-])CC#C.O=C(NCCOCCOCCOCCOCC#C)c1cc(c(c2c3ccc(cc3oc3cc(=[NH2+])ccc23)N)cc1)C(=O)[O-]

Storage Note

store at -20 °C|12 months after date of delivery