Collagen Type IV, human
Catalogue Number: CO105-EXA
| Manufacturer: | ExAlpha |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Shipping Condition: | RT |
| Storage Condition: | 2-8°C |
| Unit(s): | 1 ml |
| Host name: | Mouse |
| Clone: | COL 94 |
| Isotype: | IgG1 |
| Immunogen: | Purified human Collagen IV |
| Application: | IHC-P, WB, IHC-Fr |
Description
Description: Type IV Collagen is a non-fibrillary network of different alpha-chains: alpha 1(IV) to-alpha 6(IV). It is typically found in basal membranes of different organs (e.g. skin, lens, lung, kidney). Collagens consist of a family of highly specialized glycoproteins of which at least 16 genetically distinct types are known to date. The basal unit of a collagen molecule consists of a triple-helical structure formed by 3 alpha-chains. Predominant amino acids are glycine, proline and hydroxproline. Regularly also lysines and hydroxylysines occur, which are responsible for cross-linkage and glycosylation of the protein chains. Different composition of alpha-chains and different glycosylation contribute to the high variability of collagens in different tissues and organs. Human Collagen IV, no cross-reactivity with other Collagen types, Vitronectin, Fibronectin or Chondroitinsulfate.
Additional Text
Gene Name
COL4A1
Uniprot ID
P02462
Gene ID
1282
Concentration
100 ug/ml
Antibody Clonality
Monoclonal
Storage Note
2-8°C
Application Notes
IHC(C,P), WB
SUPPORT
outstanding technical support
PRODUCT
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DELIVERY
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