Collagen Type I, bovine
Catalogue Number: CO20121-0.1-NMB
| Manufacturer: | Nordic MuBio |
| Type: | Primary Antibody |
| Shipping Condition: | RT |
| Unit(s): | 0.1 ml |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | |
| Immunogen: | Purified collagen type I from bovine skin |
| Application: | ELISA, IF, IHC-P, WB, RIA |
Description
Description: Type I Collagen usually exists as a heterotrimer formed by alpha 1(I) and alpha 2(I) chains and is found in bone, cornea, skin and tendon. In foetal tissues also homotrimers of alpha-1(I) are found, but they are not constituents of normal adult tissues. Collagens consist of a family of highly specialized glycoproteins of which at least 16 genetically distinct types are known to date. The basal unit of a collagen molecule consists of a triple-helical structure formed by 3 alpha-chains. Predominant amino acids are glycine, proline and hydroxproline. Regularly also lysines and hydroxylysines occur, which are responsible for cross-linkage and glycosylation of the protein chains. Different composition of alpha-chains and different glycosylation contribute to the high variability of collagens in different tissues and organs. Bovine collagen type I 100%, bovine collagen II, IX, XI <0.1%; sheep collagen type I: 50 % (IHC estimated), bovine fibronectin <0.1%; human collagen type I <2%; chicken collagen type I <0.1% (estimates except sheep collagen I from solid phase RIA at dilution 1:500).
Additional Text
Gene Name
COL1A1
Concentration
0.5 mg/ml
Purification
Affinity Purified
Gene ID
282187
Uniprot ID
P02453
Storage Note
-20°C
Application Notes
IHC(P), IFA, ELISA, RIA, IB/WB
SUPPORT
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PRODUCT
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DELIVERY
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