Collagen Type I, mouse

Catalogue Number: CO20151-0.1-EXA

Manufacturer:ExAlpha
Type:Primary Antibody
Shipping Condition:RT
Unit(s): 0.1 ml
Host name: Rabbit
Clone:
Isotype:
Immunogen: Purified collagen type I from murine skin
Application: ELISA, IF, IHC-P, WB, RIA

Description

Description: Type I Collagen usually exists as a heterotrimer formed by alpha 1(I) and alpha 2(I) chains and is found in bone, cornea, skin and tendon. In foetal tissues also homotrimers of alpha-1(I) are found, but they are not constituents of normal adult tissues. Collagens consist of a family of highly specialized glycoproteins of which at least 16 genetically distinct types are known to date. The basal unit of a collagen molecule consists of a triple-helical structure formed by 3 alpha-chains. Predominant amino acids are glycine, proline and hydroxproline. Regularly also lysines and hydroxylysines occur, which are responsible for cross-linkage and glycosylation of the protein chains. Different composition of alpha-chains and different glycosylation contribute to the high variability of collagens in different tissues and organs. Mouse collagen type I 100%, mouse collagen type II and IV <0.1%; mouse collage type III <1%; .

Additional Text

Gene Name

COL1A1

Uniprot ID

P11087

Concentration

0.5 mg/ml

Purification

Affinity Purified

Gene ID

12842

Storage Note

-20°C

Application Notes

IHC(P), IFA, ELISA, RIA, IB/WB