Collagen Type IV, mouse

Catalogue Number: CO20451-0.1-EXA

Manufacturer:ExAlpha
Type:Primary Antibody
Shipping Condition:RT
Unit(s): 0.1 ml
Host name: Rabbit
Clone:
Isotype:
Immunogen: Purified collagen type IV from murine tumour tissue
Application: ELISA, IF, IHC-P, WB, RIA

Description

Description: Type IV Collagen is a non-fibrillary network of different alpha-chains: alpha 1(IV) to-alpha 6(IV). It is typically found in basal membranes of different organs (e.g. skin, lens, lung, kidney). Collagens consist of a family of highly specialized glycoproteins of which at least 16 genetically distinct types are known to date. The basal unit of a collagen molecule consists of a triple-helical structure formed by 3 alpha-chains. Predominant amino acids are glycine, proline and hydroxproline. Regularly also lysines and hydroxylysines occur, which are responsible for cross-linkage and glycosylation of the protein chains. Different composition of alpha-chains and different glycosylation contribute to the high variability of collagens in different tissues and organs. Murine collagen type IV 100%; murine collagen type I, II and III <0.1%; human collagen type IV and V <0.1%; murine fibronectin <0.1%; murine laminin <0.1% in RIA at 1:5000 dilution.

Additional Text

Gene Name

COL4A1

Concentration

0.5 mg/ml

UniProt ID

P02463

Purification

Affinity Purified

Gene ID

12826

Storage Note

-20°C

Application Notes

IHC(P), IFA, ELISA, RIA, IB/WB