Recombinant Human Sonic hedgehog protein (SHH), partial (Active)

Catalogue Number: CSB-AP000371HU-CSB

Manufacturer:Cusabio Biotech
Shelf Life:6 months
Molecular Weight:19.8 kDa
Physical state:Lyophilized
Type:Proteases
Alias:SHH
Host Cell:E.coli
Shipping Condition:Blue Ice
Unit(s): 100 ug, 5 ug, 500 ug

Description

Description: Intercellular signal essential for a variety of patterning events during development: signal produced by the notochord that induces ventral cell fate in the neural tube and somites, and the polarizing signal for patterning of the anterior-posterior axis of the developing limb bud. Displays both floor plate- and motor neuron-inducing activity. The threshold concentration of N-product required for motor neuron induction is 5-fold lower than that required for floor plate induction. Activates the transcription of target genes by interacting with its receptor PTCH1 to prevent normal inhibition by PTCH1 on the constitutive signaling activity of SMO (By similarity). {ECO:0000250}.

Additional Text

Gene Name

SHH

Uniprot ID

Q15465

Gene ID

6469

Protein Tag

Untagged

Storage Note

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Price
£697.00


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