Recombinant Human Sonic hedgehog protein(SHH) (Active)
Catalogue Number: CSB-AP000371HU-CSB
| Manufacturer: | Cusabio Biotech |
| Shelf Life: | 6 months |
| Molecular Weight: | 19.8 kDa |
| Physical state: | Lyophilized |
| Type: | Proteases |
| Alias: | SHH |
| Host Cell: | E.coli |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug, 5 ug, 500 ug |
Description
Description: Intercellular signal essential for a variety of patterning events during development: signal produced by the notochord that induces ventral cell fate in the neural tube and somites, and the polarizing signal for patterning of the anterior-posterior axis of the developing limb bud. Displays both floor plate- and motor neuron-inducing activity. The threshold concentration of N-product required for motor neuron induction is 5-fold lower than that required for floor plate induction. Activates the transcription of target genes by interacting with its receptor PTCH1 to prevent normal inhibition by PTCH1 on the constitutive signaling activity of SMO (By similarity). {ECO:0000250}.
Additional Text
Uniprot ID
Q15465
OMIN ID
135750
Protein Tag
Untagged
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