Recombinant Mouse Tumor necrosis factor receptor superfamily member 14 (Tnfrsf14), partial (Active)

Catalogue Number: CSB-AP005311MO-CSB

Manufacturer:	Cusabio Biotech
Shelf Life:	6 months
Molecular Weight:	45.6 kda
Physical state:	Lyophilized
Type:	Bioactive Proteins
Alias:	Tnfrsf14; Herpesvirus entry mediator;HVEM; TR2;TNF receptor-like molecule;ATAR;another TRAF-associated receptor;Tumor necrosis factor receptor superfamily member 14
Host Cell:	Mammalian Cells
Shipping Condition:	Blue Ice
Unit(s):	50 ug, 10 ug, 1 mg, 500 ug
Host name:
Clone:
Isotype:
Immunogen:

Overview
Datasheets

Description

Description: Mouse Protein Tnfrsf14, is a type I transmembrane protein belonging to the TNF receptor superfamily. It is tumor necrosis factor receptor superfamily member 14 and expressed on the surface of T cells during the resting state. Interaction of HVEM with TNF family member LIGHT co-stimulates T cells and promotes inflammation. HVEM also triggers inhibitory signaling cascade in effector T (Teff) cells and regulatory T cells (Tregs) as a ligand of B and T lymphocyte attenuator. Tnfrsf14 is detected in peripheral blood T cells, B cells, monocytes and in various tissues enriched in lymphoid cells. It has demonstrated that HVEM Ig is able to exert a significant antiviral effect against HSV-1 infection in vivo.

Additional Text

Uniprot ID

Q80WM9

Gene Name

TNFRSF14

Gene ID

230979

Biological Activity

The ED50 as determined by its ability to bind Human BTLA in functional ELISA is typically 1.17 ug/ml

Protein Tag

Fc Tag

Storage Note

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

CSB-AP005311MO MSDS

Price

£131.00

-

Quantity
Unit Size

Find out about delivery