Recombinant Human Liver carboxylesterase 1 (CES1)
Catalogue Number: CSB-BP005258HU-CSB
| Manufacturer: | Cusabio Biotech |
| Shelf Life: | 6 months |
| Molecular Weight: | 66.3 kDa |
| Physical state: | Liquid or Lyophilized powder |
| Type: | Other Enzymes |
| Host Cell: | Baculovirus |
| Shipping Condition: | Blue Ice |
| Unit(s): | 1 mg, 100 ug, 20 ug |
| Host name: | |
| Clone: | |
| Isotype: | |
| Immunogen: |
Description
Description: Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Hydrolyzes aromatic and aliphatic esters, but has no catalytic activity toward amides or a fatty acyl-CoA ester. Hydrolyzes the methyl ester group of cocaine to form benzoylecgonine. Catalyzes the transesterification of cocaine to form cocaethylene. Displays fatty acid ethyl ester synthase activity, catalyzing the ethyl esterification of oleic acid to ethyloleate. Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes of 2-arachidonoylglycerol and prostaglandins. Hydrolyzes cellular cholesteryl esters to free cholesterols and promotes reverse cholesterol transport (RCT) by facilitating both the initial and final steps in the process. First of all, allows free cholesterol efflux from macrophages to extracellular cholesterol acceptors and secondly, releases free cholesterol from lipoprotein-delivered cholesteryl esters in the liver for bile acid synthesis or direct secretion into the bile.
Additional Text
Gene Name
CES1
Gene ID
1066
Uniprot ID
P23141
Protein Tag
6xHIS Tag
Storage Note
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Specificity
(Acyl-coenzyme A:cholesterol acyltransferase)(ACAT)(Brain carboxylesterase hBr1)(Carboxylesterase 1)(CE-1)(hCE-1)(Cholesteryl ester hydrolase)(CEH)(Cocaine carboxylesterase)(Egasyn)(HMSE)(Methylumbelliferyl-acetate deacetylase 1)(Monocyte/macrophage serine esterase)(Retinyl ester hydrolase)(REH)(Serine esterase 1)(Triacylglycerol hydrolase)(TGH)
CSB-BP005258HU MSDS
SUPPORT
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