Recombinant Mouse [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial(Pdk1)
Catalogue Number: CSB-BP807321MO-CSB
| Manufacturer: | Cusabio Biotech |
| Shelf Life: | 6 months |
| Molecular Weight: | 48.7 kda |
| Physical state: | Liquid or Lyophilized powder |
| Type: | Kinases |
| Alias: | Pyruvate dehydrogenase kinase isoform 1 |
| Host Cell: | Baculovirus |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug, 20 ug, 1 mg |
Description
Description: Kinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle, down-regulates aerobic respiration and inhibits the formation of acetyl-coenzyme A from pyruvate. Plays an important role in cellular responses to hypoxia and is important for cell proliferation under hypoxia. Protects cells against apoptosis in response to hypoxia and oxidative stress
Additional Text
Gene Name
PDK1
Uniprot ID
Q8BFP9
Gene ID
228026
Protein Tag
10xHIS Tag
Storage Note
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
CSB-BP807321MO MSDS
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