Recombinant Human E3 ubiquitin-protein ligase ZNRF3 (ZNRF3), partial
Catalogue Number: CSB-BP890933HU-CSB
| Manufacturer: | Cusabio Biotech |
| Shelf Life: | 6 months |
| Molecular Weight: | 23.8 kDa |
| Physical state: | Liquid or Lyophilized powder |
| Type: | Transferases |
| Alias: | RING finger protein 203 Zinc/RING finger protein 3 |
| Host Cell: | Baculovirus |
| Shipping Condition: | Blue Ice |
| Unit(s): | 1 mg, 100 ug, 20 ug |
| Host name: | |
| Clone: | |
| Isotype: | |
| Immunogen: |
Description
Description: E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components Frizzled and LRP6. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone.
Additional Text
Uniprot ID
Q9ULT6
Gene ID
84133
Gene Name
ZNRF3
Protein Tag
6xHIS Tag
Storage Note
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
CSB-BP890933HU MSDS
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