Recombinant Human 5-hydroxytryptamine receptor 1B (HTR1B)

Catalogue Number: CSB-CF010882HUB2-CSB

Manufacturer:Cusabio Biotech
Shelf Life:6 months
Molecular Weight:62.1 kDa
Physical state:Liquid or Lyophilized powder
Type:Bioactive Proteins
Alias:S12 Serotonin 1D beta receptor
Host Cell:E.coli
Shipping Condition:Blue Ice
Unit(s): 100 ug, 20 ug

Description

Description: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for ergot alkaloid derivatives, various anxiolytic and antidepressant drugs and other psychoactive substances, such as lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Regulates the release of 5-hydroxytryptamine, dopamine and acetylcholine in the brain, and thereby affects neural activity, nociceptive processing, pain perception, mood and behavior. Besides, plays a role in vasoconstriction of cerebral arteries.

Additional Text

Gene ID

3351

Gene Name

HTR1B

Uniprot ID

P28222

Protein Tag

10xHIS-SUMO Tag

Storage Note

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Price
£1,731.00


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