Catalogue Number: CSB-CF010882HUB2-CSB
Manufacturer: | Cusabio Biotech |
Shelf Life: | 6 months |
Molecular Weight: | 62.1 kDa |
Physical state: | Liquid or Lyophilized powder |
Type: | Bioactive Proteins |
Alias: | S12 Serotonin 1D beta receptor |
Host Cell: | E.coli |
Shipping Condition: | Blue Ice |
Unit(s): | 100 ug, 20 ug |
Description: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for ergot alkaloid derivatives, various anxiolytic and antidepressant drugs and other psychoactive substances, such as lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Regulates the release of 5-hydroxytryptamine, dopamine and acetylcholine in the brain, and thereby affects neural activity, nociceptive processing, pain perception, mood and behavior. Besides, plays a role in vasoconstriction of cerebral arteries.
3351
HTR1B
P28222
10xHIS-SUMO Tag
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.