Recombinant Human Cannabinoid receptor 2 (CNR2), partial

Catalogue Number: CSB-EP005679HU1-CSB

Manufacturer:	Cusabio Biotech
Shelf Life:	6 months
Molecular Weight:	13.4 kDa
Physical state:	Liquid or Lyophilized powder
Type:	Other Recombinant Protein
Alias:	(CB-2)(CB2)(hCB2)(CX5)
Host Cell:	E.coli
Shipping Condition:	Blue Ice
Unit(s):	1 mg, 100 ug, 20 ug
Host name:
Clone:
Isotype:
Immunogen:

Overview
Datasheets

Description

Description: This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. May induce fusion through binding of SLC1A4 and SLC1A5 (PubMed:10708449, PubMed:12050356, PubMed:23492904).Endogenous envelope proteins may have kept, lost or modified their original function during evolution. Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. The surface protein (SU) mediates receptor recognition, while the transmembrane protein (TM) acts as a class I viral fusion protein. The protein may have at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of membranes.

Additional Text

Gene ID

1269

Uniprot ID

P34972

Gene Name

CNR2

Protein Tag

6xHIS Tag

Storage Note

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

CSB-EP005679HU1 MSDS

Price

£1,581.00

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