Catalogue Number: CSB-EP005965HU-CSB
Manufacturer: | Cusabio Biotech |
Shelf Life: | 6 months |
Molecular Weight: | 37.9 kDa |
Physical state: | Liquid or Lyophilized powder |
Type: | Fusion Protein |
Alias: | Corticotropin-releasing hormone receptor 1 ;CRH-R-1 ;CRH-R1 |
Host Cell: | E.coli |
Shipping Condition: | Blue Ice |
Unit(s): | 1 mg, 100 ug, 20 ug |
Description: G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. Inhibits the activity of the calcium channel CACNA1H. Required for normal bryonic development of the adrenal gland and for normal hormonal responses to stress. Plays a role in the response to anxiogenic stimuli.
P34998
GST Tag
104909134; 1394
122561
CRHR1, LINC02210-CRHR1
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.