Recombinant Human Corticotropin-releasing factor receptor 1 (CRHR1), partial

Catalogue Number: CSB-EP005965HU-CSB

Manufacturer:Cusabio Biotech
Shelf Life:6 months
Molecular Weight:37.9 kDa
Physical state:Liquid or Lyophilized powder
Type:Fusion Protein
Alias:Corticotropin-releasing hormone receptor 1 ;CRH-R-1 ;CRH-R1
Host Cell:E.coli
Shipping Condition:Blue Ice
Unit(s): 1 mg, 100 ug, 20 ug

Description

Description: G-protein coupled receptor for CRH (corticotropin-releasing factor) and UCN (urocortin). Has high affinity for CRH and UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. Inhibits the activity of the calcium channel CACNA1H. Required for normal bryonic development of the adrenal gland and for normal hormonal responses to stress. Plays a role in the response to anxiogenic stimuli.

Additional Text

Uniprot ID

P34998

Protein Tag

GST Tag

Gene ID

104909134; 1394

OMIN ID

122561

Gene Name

CRHR1, LINC02210-CRHR1

Storage Note

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Price
£1,162.00


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