Catalogue Number: CSB-EP009900HU-CSB
Manufacturer: | Cusabio Biotech |
Shelf Life: | 6 months |
Molecular Weight: | 28 kDa |
Physical state: | Liquid or Lyophilized powder |
Type: | Fusion Protein |
Alias: | AMPA-selective glutamate receptor 3GluR-CGluR-K3Glutamate receptor ionotropic, AMPA 3 ;GluA3 |
Host Cell: | E.coli |
Shipping Condition: | Blue Ice |
Unit(s): | 1 mg, 100 ug, 20 ug |
Description: Receptor for glutamate that functions as ligand-gated ion channel in the central nervous syst and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous syst. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
GRIA3
P42263
2892
300699
6xHIS-SUMO Tag
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.