Recombinant Human Voltage-gated potassium channel subunit beta-2 (KCNAB2)

Catalogue Number: CSB-EP012014HU-CSB

Manufacturer:Cusabio Biotech
Shelf Life:6 months
Molecular Weight:57 kDa
Physical state:Liquid or Lyophilized powder
Type:Other Enzymes
Alias:K(+) channel subunit beta-2Kv-beta-2 ;hKvbeta2
Host Cell:E.coli
Shipping Condition:Blue Ice
Unit(s): 1 mg, 100 ug, 20 ug

Description

Description: Cytoplasmic domain potassium channel subunit that modulates the characteristics of the channel-forming alpha-subunits. Contributes to the regulation of nerve signaling, and prevents neuronal hyperexcitability. Promotes expression of the pore-forming alpha subunits at the cell mbrane, and thereby increases channel activity. Promotes potassium channel closure via a mechanism that does not involve physical obstruction of the channel pore. Promotes KCNA4 channel closure. Modulates the functional properties of KCNA5. Enhances KCNB2 channel activity. Binds NADPH and has NADPH-dependent aldoketoreductase activity. Has broad substrate specificity and can catalyze the reduction of methylglyoxal, 9,10-phenanthrenequinone, prostaglandin J2, 4-nitrobenzaldehyde, 4-nitroacetophenone and 4-oxo-trans-2-nonenal (in vitro) .

Additional Text

Gene Name

KCNAB2

Uniprot ID

Q13303

Gene ID

8514

OMIN ID

601142

Protein Tag

6xHIS-SUMO Tag

Storage Note

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Price
£1,162.00


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