Catalogue Number: CSB-EP012014HU-CSB
Manufacturer: | Cusabio Biotech |
Shelf Life: | 6 months |
Molecular Weight: | 57 kDa |
Physical state: | Liquid or Lyophilized powder |
Type: | Other Enzymes |
Alias: | K(+) channel subunit beta-2Kv-beta-2 ;hKvbeta2 |
Host Cell: | E.coli |
Shipping Condition: | Blue Ice |
Unit(s): | 1 mg, 100 ug, 20 ug |
Description: Cytoplasmic domain potassium channel subunit that modulates the characteristics of the channel-forming alpha-subunits. Contributes to the regulation of nerve signaling, and prevents neuronal hyperexcitability. Promotes expression of the pore-forming alpha subunits at the cell mbrane, and thereby increases channel activity. Promotes potassium channel closure via a mechanism that does not involve physical obstruction of the channel pore. Promotes KCNA4 channel closure. Modulates the functional properties of KCNA5. Enhances KCNB2 channel activity. Binds NADPH and has NADPH-dependent aldoketoreductase activity. Has broad substrate specificity and can catalyze the reduction of methylglyoxal, 9,10-phenanthrenequinone, prostaglandin J2, 4-nitrobenzaldehyde, 4-nitroacetophenone and 4-oxo-trans-2-nonenal (in vitro) .
KCNAB2
Q13303
8514
601142
6xHIS-SUMO Tag
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.