Recombinant Human Myeloid leukemia factor 1 (MLF1)
Catalogue Number: CSB-EP014621HU-CSB
| Manufacturer: | Cusabio Biotech |
| Shelf Life: | 6 months |
| Molecular Weight: | 57.6 kDa |
| Physical state: | Liquid or Lyophilized powder |
| Type: | Cellular Proteins |
| Alias: | Myelodysplasia-myeloid leukemia factor 1 |
| Host Cell: | E.coli |
| Shipping Condition: | Blue Ice |
| Unit(s): | 1 mg, 100 ug, 20 ug |
| Host name: | |
| Clone: | |
| Isotype: | |
| Immunogen: |
Description
Description: Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.
Additional Text
Gene Name
MLF1
Gene ID
4291
Uniprot ID
P58340
Protein Tag
GST Tag
OMIN ID
601402
Storage Note
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
CSB-EP014621HU MSDS
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations