Recombinant Human Protein phosphatase 1A (PPM1A)
Catalogue Number: CSB-EP018489HU-CSB
| Manufacturer: | Cusabio Biotech |
| Shelf Life: | 6 months |
| Molecular Weight: | 69.3 kDa |
| Physical state: | Liquid or Lyophilized powder |
| Type: | Protein Phosphatases |
| Alias: | Protein phosphatase 2C isoform alpha |
| Host Cell: | E.coli |
| Shipping Condition: | Blue Ice |
| Unit(s): | 1 mg, 100 ug, 20 ug |
| Host name: | |
| Clone: | |
| Isotype: | |
| Immunogen: |
Description
Description: Enzyme with a broad specificity. Negatively regulates TGF-beta signaling through dephosphorylating SMAD2 and SMAD3, resulting in their dissociation from SMAD4, nuclear export of the SMADs and termination of the TGF-beta-mediated signaling. Dephosphorylates PRKAA1 and PRKAA2. Plays an important role in the termination of TNF-alpha-mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB.
Additional Text
Gene Name
PPM1A
Gene ID
5494
Uniprot ID
P35813
Protein Tag
GST Tag
OMIN ID
606108
Storage Note
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
CSB-EP018489HU MSDS
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