Recombinant Human Transient receptor potential cation channel subfamily A member 1 (TRPA1), partial

Catalogue Number: CSB-EP025074HU-CSB

Manufacturer:Cusabio Biotech
Shelf Life:6 months
Molecular Weight:35.2 kda
Physical state:Liquid or Lyophilized powder
Type:Fusion Protein
Alias:Ankyrin-like with transmembrane domains protein 1 Transformation-sensitive protein p120
Host Cell:E.coli
Shipping Condition:Blue Ice
Unit(s): 1 mg, 100 ug, 20 ug

Description

Description: Receptor-activated non-selective cation channel involved in detection of pain and possibly also in cold perception and inner ear function (PubMed:25389312, PubMed:25855297). Has a central role in the pain response to endogenous inflammatory mediators and to a diverse array of volatile irritants, such as mustard oil, cinnamaldehyde, garlic and acrolein, an irritant from tears gas and vehicule exhaust fumes (PubMed:25389312, PubMed:20547126). Is also activated by menthol (in vitro)(PubMed:25389312). Acts also as a ionotropic cannabinoid receptor by being activated by delta(9)-tetrahydrocannabinol (THC), the psychoactive component of marijuana (PubMed:25389312). May be a component for the mechanosensitive transduction channel of hair cells in inner ear, thereby participating in the perception of sounds. Probably operated by a phosphatidylinositol second messenger system (By similarity).

Additional Text

Gene Name

TRPA1

Gene ID

8989

Uniprot ID

O75762

OMIN ID

604775

Protein Tag

6xHIS-SUMO Tag

Storage Note

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Price
£1,581.00


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