Recombinant Bovine coronavirus Spike glycoprotein(S),partial

Catalogue Number: CSB-EP322803BJK-CSB

Manufacturer:Cusabio Biotech
Shelf Life:12 months
Molecular Weight:27.2 kDa
Physical state:Liquid or Lyophilized powder
Type:Fusion Protein
Alias:E2 Peplomer protein
Shipping Condition:Blue Ice
Unit(s): 1 mg, 100 ug, 20 ug


Description: S1 attaches the virion to the cell membrane by binding to 9-O-acetylated sialic acid containing proteins, initiating the infection. S2 is a class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes

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