Catalogue Number: CSB-EP333052BJO-CSB
|Shelf Life:||12 months|
|Molecular Weight:||27.7 kDa|
|Physical state:||Liquid or Lyophilized powder|
|Host Cell:||E. Coli|
|Shipping Condition:||Blue Ice|
|Unit(s):||1 mg, 100 ug, 20 ug|
Description: S1 attaches the virion to the cell mbrane by binding to 9-O-acetylated sialic acid containing proteins, initiating the infection.S2 is a class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell mbrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell mbranes .