Recombinant Human Trichoplein keratin filament-binding protein(TCHP)
Catalogue Number: CSB-EP874804HU-CSB
| Manufacturer: | Cusabio Biotech |
| Shelf Life: | 6 months |
| Molecular Weight: | 77.1 kDa |
| Physical state: | Liquid or Lyophilized powder |
| Type: | Fusion Protein |
| Alias: | Mitochondrial protein with oncostatic activity ;Mitostatin;Tumor suppressor protein |
| Host Cell: | E.coli |
| Shipping Condition: | Blue Ice |
| Unit(s): | 1 mg, 100 ug, 20 ug |
Description
Description: Tumor suppressor which has the ability to inhibit cell growth and be pro-apoptotic during cell stress. Inhibits cell growth in bladder and prostate cancer cells by a down-regulation of HSPB1 by inhibiting its phosphorylation. May act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery. May regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells.
Additional Text
Uniprot ID
Q9BT92
OMIN ID
612654
Protein Tag
6xHIS-SUMO Tag
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