Recombinant Human 1-acylglycerol-3-phosphate O-acyltransferase PNPLA3 (PNPLA3), partial

Catalogue Number: CSB-EP889106HU-CSB

Manufacturer:	Cusabio Biotech
Shelf Life:	6 months
Molecular Weight:	53.7 kda
Physical state:	Liquid or Lyophilized powder
Type:	Transferases
Alias:	(Acylglycerol transacylase)(Adiponutrin)(ADPN)(Calcium-independent phospholipase A2-epsilon)(iPLA2-epsilon)(Lysophosphatidic acid acyltransferase)(Patatin-like phospholipase domain-containing protein 3)
Host Cell:	E.coli
Shipping Condition:	Blue Ice
Unit(s):	1 mg, 100 ug, 20 ug
Host name:
Clone:
Isotype:
Immunogen:

Overview
Datasheets

Description

Description: Specifically catalyzes coenzyme A (CoA)-dependent acylation of 1-acyl-sn-glycerol 3-phosphate (2-lysophosphatidic acid/LPA) to generate phosphatidic acid (PA), an important metabolic intermediate and precursor for both triglycerides and glycerophospholipids. Does not esterify other lysophospholipids. Acyl donors are long chain (at least C16) fatty acyl-CoAs: arachidonoyl-CoA, linoleoyl-CoA, oleoyl-CoA and at a lesser extent palmitoyl-CoA. Additionally possesses low triacylglycerol lipase and CoA-independent acylglycerol transacylase activities and thus may play a role in acyl-chain remodeling of triglycerides. Has hydrolytic activity against glycerolipids triacylglycerol, diacylglycerol and monoacylglycerol, with a strong preference for oleic acid as the acyl moiety. Possesses phospholipase A2 activity.

Additional Text

Gene ID

80339

Uniprot ID

Q9NST1

Gene Name

PNPLA3

Protein Tag

10xHIS Tag, Myc Tag

Storage Note

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

CSB-EP889106HU MSDS

Price

£1,581.00

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