CD14 Monoclonal Antibody,PE-Cy5 Conjugated

Catalogue Number: CSB-MA072336-CSB

Manufacturer:Cusabio Biotech
Preservative:0.09% Sodium azide
Ph:7.4
Physical state:Liquid
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone:
Isotype: IgG1
Immunogen: Recombinant Protein
Application: ELISA, FC, IF

Description

Description: 4AW4 reacts with CD14, a 53-55 kDa molecule. CD14 is a human high affinity cell-surface receptor for complexes of lipopolysaccharide (LPS-endotoxin) and serum LPS-binding protein (LPB). CD14 antigen has a strong presence on the surface of monocytes/macrophages, is weakly expressed on granulocytes, but not expressed by myeloid progenitor cells. CD14 functions as a receptor for endotoxin; when the monocytes become activated they release cytokines such as TNF, and up-regulate cell surface molecules including adhesion molecules.This clone is cross reactive with non-human primate.1. Knapp, W et al., eds. (1989) Leucocyte Typing IV: White Cell Differentiation Antigens, Oxford University Press, New York.2. Makgoba, MW et al., (1988) Nature 331: 86-883. Boyd. AW et al. (1989) Blood 73: 1896-1903

Additional Text

Gene Name

CD14

Gene ID

929

Purification

Affinity Purified

Uniprot ID

P08571

Antibody Clonality

Monoclonal