Catalogue Number: CSB-MA072336-CSB
Manufacturer: | Cusabio Biotech |
Preservative: | 0.09% Sodium azide |
Ph: | 7.4 |
Physical state: | Liquid |
Type: | Monoclonal Primary Antibody - Conjugated |
Shipping Condition: | Blue Ice |
Unit(s): | 100 ul |
Host name: | Mouse |
Clone: | |
Isotype: | IgG1 |
Immunogen: | Recombinant Protein |
Application: | ELISA, FC, IF |
Description: 4AW4 reacts with CD14, a 53-55 kDa molecule. CD14 is a human high affinity cell-surface receptor for complexes of lipopolysaccharide (LPS-endotoxin) and serum LPS-binding protein (LPB). CD14 antigen has a strong presence on the surface of monocytes/macrophages, is weakly expressed on granulocytes, but not expressed by myeloid progenitor cells. CD14 functions as a receptor for endotoxin; when the monocytes become activated they release cytokines such as TNF, and up-regulate cell surface molecules including adhesion molecules.This clone is cross reactive with non-human primate.1. Knapp, W et al., eds. (1989) Leucocyte Typing IV: White Cell Differentiation Antigens, Oxford University Press, New York.2. Makgoba, MW et al., (1988) Nature 331: 86-883. Boyd. AW et al. (1989) Blood 73: 1896-1903
CD14
929
Affinity Purified
P08571
Monoclonal