CD4 Monoclonal Antibody,PE Conjugated

Catalogue Number: CSB-MA260243-CSB

Manufacturer:Cusabio Biotech
Preservative:0.09% Sodium azide
Ph:7.4
Physical state:Liquid
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone:
Isotype: IgG2b
Immunogen: Recombinant Protein
Application: ELISA, FC, IF

Description

Description: CD4, also known as T4, is a 55 kD single chain transmembrane glycoprotein and belongs to immunoglobulin superfamily. CD4 is found on most thymocytes, a subset of T cells and at low level on monocytes/macrophages.CD4 is a co-receptor involved in immune response (co-receptor activity in binding to MHC class II molecules) and HIV infection (CD4 is primary receptor for HIV-1 surface glycoprotein gp120). CD4 regulates T-cell activation, T/B-cell adhesion, T-cell diferentiation, T-cell selection and signal transduction.1. Ledbetter, J et al. (1981) J Exp Med 153:310-323.2. Haynes , B et al. (1986) Leukocyte Typing II: Human T lymphocytes. New York: Sprimger-Verlag; 3-30.3. Clevers H et al. (1988). Ann Rev Immunol 6 : 629-662.4. Barclay, N et al. (1993). The Leucocyte Factsbook. Academic Press. San Diego.

Additional Text

Gene Name

CD4

Gene ID

920

Uniprot ID

P01730

Purification

Affinity Purified

Antibody Clonality

Monoclonal