FCGR3A Monoclonal Antibody,PE Conjugated

Catalogue Number: CSB-MA279768-CSB

Manufacturer:Cusabio Biotech
Preservative:0.09% sodium azide
Ph:7.4
Physical state:Liquid
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone:
Isotype: IgG1
Immunogen: Recombinant Protein
Application: ELISA, FC, IF

Description

Description: COC16 reacts with human CD16, a 50-65 kDa Fcg receptor IIIa (FcgRIII), expressed on NK cells, monocytes/macrophages and granulocytes. It is a human NK cell associated antigen. CD16 is a low affinity receptor for IgG which functions in phagocytosis and ADCC, as well as in signal transduction and NK cell activation. The CD16 antibody blocks the binding of soluble immune complexes to granulocytes.This clone is cross reactive with non-human primate.1. Knapp, W.,et al. (1989) Leucocyte Typing IV: White Cell Differentiation Antigens, Oxford University Press, New York.2. Stroncek, D.F., et al. (1991) Blood 77:1572.3. Wirthmueller, U., et al. (1992) J. Exp. Med. 175:1381.4. Barclay, N.A., et al. (1993) The Leucocyte Antigen FactBook, CD16 section, Academic Press Inc.,San Diego, Calfornia, p. 136.

Additional Text

Gene ID

2214

Gene Name

FCGR3A

Purification

Affinity Purified

Uniprot ID

P08637

Storage Note

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Antibody Clonality

Monoclonal