Catalogue Number: CSB-MA570802-CSB
Manufacturer: | Cusabio Biotech |
Preservative: | 0.09% Sodium azide |
Ph: | 7.4 |
Physical state: | Liquid |
Type: | Monoclonal Primary Antibody - Conjugated |
Shipping Condition: | Blue Ice |
Unit(s): | 100 ul |
Host name: | Mouse |
Clone: | |
Isotype: | IgG2b |
Immunogen: | Recombinant Protein |
Application: | ELISA, FC, IF |
Description: CD4, also known as T4, is a 55 kD single chain transmembrane glycoprotein and belongs to immunoglobulin superfamily. CD4 is found on most thymocytes, a subset of T cells and at low level on monocytes/macrophages.CD4 is a co-receptor involved in immune response (co-receptor activity in binding to MHC class II molecules) and HIV infection (CD4 is primary receptor for HIV-1 surface glycoprotein gp120). CD4 regulates T-cell activation, T/B-cell adhesion, T-cell diferentiation, T-cell selection and signal transduction.1. Ledbetter, J et al. (1981) J Exp Med 153:310-323.2. Haynes , B et al. (1986) Leukocyte Typing II: Human T lymphocytes. New York: Sprimger-Verlag; 3-30.3. Clevers H et al. (1988). Ann Rev Immunol 6 : 629-662.4. Barclay, N et al. (1993). The Leucocyte Factsbook. Academic Press. San Diego.
CD4
920
P01730
Affinity Purified
Monoclonal